Endocrine Abstracts

Aim: Increased thyroid volume and thyroid dysfunction (TD) in diabetics have been reported. The aim of this study is to investigate the prevalence of thyroid disorders in patients with type 2 diabetes mellitus in formerly iodine deficient area.Methods: We included 131 (73 females and 58 males) diabetics without a history of previous thyroid disease and symptoms. The demographic, medical and clinical data, laboratory results (fasting plasma glucose (FPG),...

Introduction and aims: Polycystic ovary syndrome (PCOS) is a frequent endocrinopathy among with young women. It is known that insulin resistance is encountered in the vast majority of the women with PCOS and hence the risk of type 2 diabetes mellitus and coronary artery disease are increased. These cardiac and metabolic risk increments may also associated with hyperandrogenemia and dyslipidemia. The metabolic changes of lipid profiles in young women with PCOS are not completel...

Introduction: The aim of this study, left ventricular systolic and diastolic function by echocardiography and tissue Doppler echocardiographic evaluation and relationship serum N-terminal pro-B-type brain natriuretic peptide (NT-proBNP) levels of women with polycystic ovary syndrome (PCOS).Materials and method: Thirty-two women with PCOS (age: 23.4–4.6 years; BMI: 23.8–4.8 kg/m2), similar age and BMI have features 30 healthy womens c...

Introduction: We present a case investigated due to hypokalemia and diagnosed as rectal neuroendocrine tumor-related EAS.Case: A 67-year-old woman with weight loss and symptoms of lethargy, abdominal pain was referred due to low serum K+ levels. Elevated blood pressure and a rectal mass were detected at physical examination. Low serum K+, elevated ALT levels, lymphopenia, neutrophilia and metabolic alkalosis were present. Computed t...

Introduction and objective: Cardiovascular mortality is high in acromegaly. Our aim in this study was to determine the levels of the new cardiovascular marker in active acromegaly patients, the mean platelet volume (MPV) values before and after octreotide acetate long-acting repeatable treatment.Material and methods: Thirty-six patients with active acromegaly who presented at the Endocrinology Department (mean age 46.0±14.0 years and mean BMI: 30.4&...

Aim: Hashimoto’s thyroiditis (HT) is an autoimmune disease in which a breakdown of immune tolerance is caused by interplay of a variety of immunologic, genetic, and environmental factors. Mean platelet volume (MPV) is the measure of platelet size. MPV possibly is a simple way to estimate platelet activity. Activated platelets play an important role in the pathogenesis of vascular disease especially coronary heart diseases. Larger platelets are metabolically and enzymatica...

Introduction: There have been no studies on the prevalence of primary aldosteronism (PA) in Turkey. In this study, the prevalence of PA among the hypertensive population was investigated.Methods/Design: The study was conducted among hypertensive patients, aged 16–88 years, who visited the out-patient clinic of Endocrinology from January 10th, 2011 to September 30th, 2011. 768 of the 774 consecutive hypertensive patients volunteered to participate. T...

Introduction and aims: It is known that obesity is associated with retinal microvascular changes. Optical coherence tomography (OCT), a new imaging technique, is used to visualize the choroid. In addition, OCT can also give more beneficial information about systemic and eye diseases. We aim to investigate whether or not obesity may impact on choroid and macula thickness.Material and methods: Forty-four subjects who were apply for obesity in our Endocrino...

Introduction: Permanent hypothyroidism is a common side effect of thyroidectomy. Thyroxine binding globulin (TBG) deficiency is characterized with low total thyroid hormones (TH) in the presence of normal free THs and thyroid stimulating hormone (TSH).Case report: A previously healthy 37-year-old man underwent annual health check-up. Thyroid US revealed a 24×14×19 mm isoechoic solid nodule in the left lobe. TSH was 1.4 (0.27–4.2 μIU/m...

Introduction: Congenital hyperinsulinism (CHI), is the most frequent cause of persistent hypoglycemia in infancy. Mutations in the ABCC8 gene are responsible for 40–50% of CHI cases. Its management can be extremely complicated. The main goal of the treatment is to maintain normoglycemia, since hypoglycemia during infancy can have severe neurological consequences. Herein, we report 8 year follow up of twin patients who were diagnosed with CHI at neonatal period due to SUR1...